Bioavailability and bioequivalence are key concepts in pharmacology and the pharmaceutical industry, particularly when it comes to how drugs are absorbed, distributed, and utilized in the body. Both terms are closely related to the effectiveness and safety of drugs, especially when comparing different formulations of the same drug.
Bioavailability refers to the proportion of a drug that enters the bloodstream when it is introduced into the body and is made available for therapeutic action. It is a critical measure of the extent and rate at which the active drug ingredient is absorbed and becomes available at the site of action (i.e., where the drug exerts its therapeutic effects).In simple terms, bioavailability tells us how much of the drug actually reaches the bloodstream and is available to have its effect after being taken by the patient.